GO:0097161 molecular_function DH domain binding
| PAG Title | GO:0097161 molecular_function DH domain binding |
| PAG ID | TAX030715 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket. |
| Species | Homo sapiens |
| nCoCo Score | 0 |
| Base PAG ID | TAX030715 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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